Eye drops could replace needles for blinding eye disease?
NCT ID NCT06969001
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage trial tested the safety of SCAI-005, an eye drop containing axitinib, in 48 healthy Korean adults. The goal was to see if the drug is safe and how it behaves in the body when given as single or multiple doses. It is a first step toward a potential needle-free treatment for wet age-related macular degeneration, a leading cause of vision loss.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- axitinib (as eye drops)
- What this could lead to
- If this early safety study succeeds, it could pave the way for a non-invasive eye drop treatment for wet age-related macular degeneration, potentially reducing the need for frequent injections.
- What could go wrong
- This is a very early Phase 1 trial in only 48 healthy people, not patients with the disease. It only tests safety and how the drug moves through the body, not whether it works for wet AMD. Many drugs fail in later stages.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Catholic University, Seoul ST. Mary's Hospital
Seoul, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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