Could eye drops replace injections for a leading cause of blindness?
NCT ID NCT07764965
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This early-stage trial is evaluating the safety, tolerability, and how the body absorbs PAN-90806, an experimental eye drop being developed for wet age-related macular degeneration (AMD), a leading cause of vision loss. Healthy adults aged 18 to 50 will receive either PAN-90806 or a placebo eye drop once daily in both eyes for six days. Researchers will monitor participants for side effects and measure drug levels in the blood, along with eye exams and other health checks, to see if the treatment is safe enough to study further.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PAN-90806 ophthalmic solution (eye drops)
- What this could lead to
- If safe and well-tolerated, PAN-90806 eye drops could become a non-invasive treatment option for wet age-related macular degeneration, potentially reducing the need for frequent eye injections.
- What could go wrong
- This is an early Phase 1 study in a small group of healthy volunteers, so it cannot yet determine if the drug works for the disease. Potential risks include eye irritation or other side effects, and the drug may not perform as hoped in later trials.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NEOVASCULAR (WET) AGE-RELATED MACULAR DEGENERATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a daily eye gel replace injections for wet AMD?
- New eye injection could reduce treatment frequency for wet AMD
- New study aims to keep macular disease patients on track with eye injections
- New eye injection could mean fewer doctor visits for wet AMD patients
- Eye injection burden varies by disease, study finds
- New syringe for eye disease injections passes usability test