New radiation approach may delay need to switch cancer drugs in advanced breast cancer

NCT ID NCT06260033

Recruiting now Disease control Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 28 times

Summary

This study tests whether a precise type of radiation (SBRT) can allow people with estrogen receptor-positive (ER+) breast cancer that has spread and is starting to grow again to keep using their current medication instead of switching to a new one. About 18 participants will receive SBRT to their growing tumors and be monitored with special PET scans (FES PET/CT) to see how well the cancer is controlled. The goal is to see if this approach can extend the time before a treatment change is needed.

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Contacts and locations

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Locations

City of Hope Medical Center
RECRUITING

Duarte, California, 91010, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
City of Hope at Irvine Lennar
RECRUITING

Irvine, California, 92618, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact

Conditions

Explore the condition pages connected to this study.

ANATOMIC STAGE IV BREAST CANCER AJCC V8 ESTROGEN RECEPTOR-POSITIVE BREAST CARCINOMA METASTATIC BREAST CARCINOMA