New hope for PMR sufferers: drug combo aims to reduce steroid use

NCT ID NCT07286214

Not yet recruiting Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Jan 05, 2026 · Last updated May 11, 2026 · Updated 24 times

Summary

This study tests whether adding the drug sarilumab to a slow steroid taper helps adults with early polymyalgia rheumatica (PMR) achieve lasting remission. About 300 people aged 50 and older will receive either sarilumab or a placebo, along with a 52-week steroid reduction plan. The goal is to see if sarilumab can control the disease better than steroids alone, while reducing side effects.

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