Shorter radiation may cut arm swelling in breast cancer patients

NCT ID NCT02912312

First seen Jan 11, 2026 · Last updated Apr 29, 2026 · Updated 16 times

Summary

This study compares a 3-week course of radiation to the standard 5-week course for people with invasive breast cancer who need radiation to the lymph nodes near the breast. The goal is to see if the shorter treatment reduces arm swelling (lymphedema) while keeping the cancer from coming back. About 805 participants will be randomly assigned to one of the two radiation schedules.

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Contacts and locations

Locations

  • Baptist - MD Anderson Cancer Center

    Jacksonville, Florida, 32207, United States

  • Community MD Anderson Cancer Center East

    Indianapolis, Indiana, 46219, United States

  • Community MD Anderson Cancer Center North

    Indianapolis, Indiana, 49625, United States

  • Community MD Anderson Cancer Center South

    Indianapolis, Indiana, 46227, United States

  • Cooper Hospital University Medical Center

    Camden, New Jersey, 08103, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • MD Anderson Cancer Center (Banner)

    Gilbert, Arizona, 85234, United States

  • MD Anderson Cancer Center (Banner)- Northern Colorado

    Greeley, Colorado, 80631, United States

  • Ohio Health

    Columbus, Ohio, 43215, United States

  • Orlando Health Cancer Institute

    Orlando, Florida, 32806, United States

  • Scripps- MD Anderson Cancer

    San Diego, California, 92121, United States

  • UT Health San Antonio - MD Anderson Cancer Center

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.