Saliva test may reveal hidden spread of oral cancer
NCT ID NCT07692360
First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study investigates whether substances in saliva, specifically interleukin-6 levels and certain gene variations, can indicate whether oral cancer has spread to lymph nodes in the neck. Researchers will collect saliva samples from adults with oral squamous cell carcinoma before they begin treatment. The goal is to find biological markers that could help doctors better understand and predict the behavior of the cancer, potentially leading to more personalized treatment plans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple saliva test that helps doctors determine how aggressive an oral cancer is and guide treatment decisions.
- What could go wrong
- This is a small, early observational study. The markers may not prove reliable enough for clinical use, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Maxillo-Facial Surgery and Dental Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
Milan, Lombardy, 20122, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia
Pavia, Lombardy, 27100, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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