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Could a Cell-Cycle protein reveal how aggressive oral cancer is?

NCT ID NCT07778615

Knowledge-focused Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This study looks at tissue samples from 34 people with oral squamous cell carcinoma to measure levels of a protein called cyclin D1, which helps cells divide. The goal is to see whether higher cyclin D1 levels are linked to patient age, sex, tumor location, grade, or signs of invasion. If a link is found, cyclin D1 might one day help doctors predict how aggressive a tumor is.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Immunohistochemical analysis of cyclin D1 protein in tumor tissue samples
What this could lead to
If cyclin D1 levels correlate with aggressive tumor features, it could become a marker to help predict how oral cancer will behave.
What could go wrong
This is a small, observational study, so any link found may not hold up in larger groups. It only looks at tissue samples, not treatments or outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

34 people

The number who actually took part.

Started

Jan 2017

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

a retrospective, observational study

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients with oral squamous cell carcinoma. Exclusion Criteria: * patients with oral carcinoma other than squamous cell carcinoma. * patients who received pre-operative radiotherapy. * patients with inadequate clinical data.

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Conditions

The condition(s) this trial relates to.

oral cavity squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Oral squamous cell carcinoma (OSCC)

Contacts and locations

Locations

  • Study site

    Sohag, Egypt

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Other studies related to the condition(s) this trial covers.