New drug targets Hard-to-Treat tumors in early trial

NCT ID NCT05735366

First seen Mar 15, 2026 · Last updated May 13, 2026 · Updated 5 times

Summary

This early-phase study tested a new drug called SAIL66 in 22 adults with advanced solid tumors that have a specific protein (CLDN6). The main goals were to check safety, find the right dose, and see if the drug can shrink tumors. Participants received the drug by infusion, and researchers monitored side effects and tumor response.

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Contacts and locations

Locations

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • Cancer Institute Hospital of JFCR

    Tokyo, Koto Ku, 135-8550, Japan

  • Georgia Cancer Center at Augusta University

    Augusta, Georgia, 30912, United States

  • MUSC Hollings Cancer Center

    Charleston, South Carolina, 29425, United States

  • National Cancer Center Hospital

    Tokyo, Chuo Ku, 104-0045, Japan

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan

  • Shizuoka Cancer Center

    Shizuoka, Sunto-gun, 411-8777, Japan

  • Tennessee Oncology, PLLC

    Nashville, Tennessee, 37203, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.