New targeted drug shows early promise for Hard-to-Treat cancers

NCT ID NCT05735366

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tested a new drug called SAIL66 in 22 adults with advanced solid tumors that have a specific protein (CLDN6). The main goals were to check safety, find the right dose, and see if the drug can shrink tumors. While not a cure, the approach aims to control the disease in patients who have limited options.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • Cancer Institute Hospital of JFCR

    Tokyo, Koto Ku, 135-8550, Japan

  • Georgia Cancer Center at Augusta University

    Augusta, Georgia, 30912, United States

  • MUSC Hollings Cancer Center

    Charleston, South Carolina, 29425, United States

  • National Cancer Center Hospital

    Tokyo, Chuo Ku, 104-0045, Japan

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan

  • Shizuoka Cancer Center

    Shizuoka, Sunto-gun, 411-8777, Japan

  • Tennessee Oncology, PLLC

    Nashville, Tennessee, 37203, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States