New MS drug candidate enters early safety testing

NCT ID NCT05704361

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This early-stage study is testing a new drug called RO7121932 in 129 people with multiple sclerosis (MS). The goal is to check if the drug is safe and how the body handles it when given as a single or multiple doses, either through a vein or under the skin. Participants are not on other MS treatments during the study. The results will help decide if further testing is warranted.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

Contacts and locations

Locations

ARENSIA Exploratory Medicine Phase I, PMSI Republican Clinical Hospital
COMPLETED

Chisinau, MD-2025, Moldova
ARENSIA Exploratory Medicine SRL - Bucharest (Monza Medical Center)
RECRUITING

Bucharest, 011658, Romania
ARENSIA Exploratory Medicine, County Emergency Hospital
RECRUITING

Cluj-Napoca, 40006, Romania
Centro Hospitalar Entre o Douro e Vouga E.P.E. - Hospital de São Sebastião
RECRUITING

Santa Maria da Feira, 4520-211, Portugal
Cliniques Universitaires St-Luc
RECRUITING

Brussels, 1200, Belgium
Fond. Istituto Neurologico C.Besta
RECRUITING

Milan, Lombardy, 20133, Italy
Hadassah University Hospital - Ein Kerem
RECRUITING

Jerusalem, 9112001, Israel
Hospital Santo Antonio dos Capuchos
RECRUITING

Lisbon, 1169-050, Portugal
Hospital Universitari Vall dHebron (CEMCAT)
RECRUITING

Barcelona, 08035, Spain
Hospital de Braga
RECRUITING

Braga, 4710-243, Portugal
IRCCS Ospedale San Raffaele
RECRUITING

Milan, Lombardy, 20132, Italy
Instytut Psychiatrii i Neurologii II Klinika Neurologiczna
WITHDRAWN

Warsaw, 02-957, Poland
Klinikum rechts der Isar der TU Muenchen
COMPLETED

München, 81675, Germany
MedPolonia
RECRUITING

Poznan, 60-693, Poland
Montreal Neurological Institute and Hospital
RECRUITING

Montreal, Quebec, H3A 2B4, Canada
Osrodek Badan Klinicznych Euromedis
RECRUITING

Szczecin, 70-111, Poland
Regionalny Szpital Specjalistyczny im. W. Bieganskiego
COMPLETED

Grudzi?dz, 86-300, Poland
SPSK nr 1
COMPLETED

Zabrze, 41-800, Poland
Stanford University Medical Center
COMPLETED

Stanford, California, 94305, United States
Tel Aviv Sourasky Medical Center
WITHDRAWN

Tel Aviv, 6423906, Israel
UC Health, LLC.
WITHDRAWN

Cincinnati, Ohio, 45267, United States
UZ Gent
RECRUITING

Ghent, 9000, Belgium
University Clinical Center of Serbia
RECRUITING

Belgrade, 11000, Serbia
University of Massachusetts Medical School
WITHDRAWN

Worcester, Massachusetts, 01655, United States
University of South Florida
WITHDRAWN

Tampa, Florida, 33612, United States
Universitätsklinikum "Carl Gustav Carus"
ACTIVE_NOT_RECRUITING

Dresden, 01307, Germany
Universitätsklinikum Münster Klinik u. Poliklinik f. Neurologie
RECRUITING

Münster, 48149, Germany
Universitätsklinikum Tübingen, Zentrum für Neurologie
RECRUITING

Tübingen, 72076, Germany
Universitätsklinikum Ulm
RECRUITING

Ulm, 89081, Germany
Universitätsmedizin Göttingen Georg-August-Universität
COMPLETED

Göttingen, 37075, Germany
Uniwersyteckie Centrum Kliniczne
WITHDRAWN

Gda?sk, 80-214, Poland
Yale University Multiple Sclerosis Center
COMPLETED

New Haven, Connecticut, 06473, United States

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