New drug duo targets stubborn breast cancer before surgery

NCT ID NCT05675579

First seen Nov 05, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tests whether giving two drugs—sacituzumab govitecan and pembrolizumab—before surgery can help control early-stage triple-negative breast cancer that didn't respond well to initial chemotherapy. About 27 adults with this aggressive cancer type will receive the combination. The goal is to see if this approach improves outcomes and is safe.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.