Promising drug trodelvy tested as first defense against aggressive breast cancer

NCT ID NCT07299409

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing the drug sacituzumab govitecan (Trodelvy) as a first treatment for people with advanced triple-negative breast cancer who haven't had prior therapy for advanced disease. Researchers want to see if the drug can shrink tumors or slow the cancer's growth. The study will also compare how well the drug works in different genetic subtypes of the cancer. About 24 adults will take part, receiving the drug intravenously on days 1 and 8 of each 21-day cycle.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sacituzumab govitecan (Trodelvy)

What this could lead to

If successful, this could provide a new first-line treatment option for advanced triple-negative breast cancer, potentially slowing disease progression.

What could go wrong

This is a small, early-phase (Phase 2) study with only 24 participants, so results may not apply to all patients. The drug may cause side effects like nausea, diarrhea, or low blood cell counts.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BC Cancer - Vancouver Center

    Vancouver, British Columbia, V5Z 4E6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact