New drug cocktail targets tough cancers in early trial
NCT ID NCT04826341
First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 9 times
Summary
This study tests a combination of two drugs, sacituzumab govitecan and berzosertib, in adults with small cell lung cancer or cancers that have stopped responding to PARP inhibitors. The goal is to find a safe dose and see if the combo can shrink tumors. Participants receive the drugs by IV on specific days of a 21-day cycle, and treatment continues as long as it helps and is tolerated.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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Other studies related to the condition(s) this trial covers.
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