New hope for rare leukemia: drug aims to control disease and delay progression

NCT ID NCT03722407

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This study tests whether the drug ruxolitinib can help people with chronic myelomonocytic leukemia (CMML), a rare blood cancer. About 29 adults will receive the drug to see if it improves blood counts, shrinks the cancer, or keeps it stable. The goal is to control the disease and delay it from turning into a more aggressive leukemia.

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Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

    Baltimore, Maryland, 21231, United States

  • Weill Medical College of Cornell University

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.