Promising cream for painful skin condition tested in tiny trial
NCT ID NCT04414514
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small, early trial tested a cream called ruxolitinib 1.5% on 6 people with early-stage hidradenitis suppurativa, a painful skin condition that causes lumps and abscesses. The goal was to see if the cream could reduce inflammation and improve symptoms after 16 weeks. However, the study was terminated early, so we have very limited information about its effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ruxolitinib 1.5% cream
What this could lead to
If it works, this could point toward a topical treatment for early-stage hidradenitis suppurativa, reducing painful lumps and inflammation.
What could go wrong
This was a very small, early-phase trial that was terminated early, so results are limited. It is unclear if the cream will work for most people or have side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Penn State Hershey Medical Center
Hershey, Pennsylvania, 17033, United States