New cream could ease painful skin bumps for HS sufferers

NCT ID NCT06958211

Ongoing Symptom relief Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This study tests a cream called ruxolitinib for people with mild to moderate hidradenitis suppurativa (HS), a condition causing painful bumps under the skin. About 550 adults with HS will use the cream or a placebo for several weeks to see if it reduces flare-ups and improves symptoms. The goal is to find a topical treatment that can ease this chronic skin condition without strong side effects.

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Conditions

The condition(s) this trial relates to.

hidradenitis suppurativa skin disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIDRADENITIS SUPPURATIVA

Contacts and locations

Locations

Investigative Site BE201

Ghent, 09000, Belgium
Investigative Site BE202

Leuven, 03000, Belgium
Investigative Site BE203

Ghent, 09000, Belgium
Investigative Site BE204

Brussels, 01070, Belgium
Investigative Site BG201

Sevlievo, 05400, Bulgaria
Investigative Site BG202

Sofia, 01431, Bulgaria
Investigative Site BG203

Sofia, 01592, Bulgaria
Investigative Site CA201

Winnipeg, Manitoba, R3M 3Z4, Canada
Investigative Site CA202

Hamilton, Ontario, L8L 3C3, Canada
Investigative Site CA203

London, Ontario, N6H 5L5, Canada
Investigative Site CA204

Markham, Ontario, L3P 1X3, Canada
Investigative Site CA205

Mississauga, Ontario, L4W 0C2, Canada
Investigative Site CA206

St. John's, A1E 1V4, Canada
Investigative Site CA207

Fredericton, New Brunswick, E3B 1G9, Canada
Investigative Site CA208

Saskatoon, Saskatchewan, S7K 0H6, Canada
Investigative Site CA209

Edmonton, Alberta, T5K1X3, Canada
Investigative Site DE202

Hanover, 30159, Germany
Investigative Site DE203

Kiel, 24105, Germany
Investigative Site DE204

Merzig, 66663, Germany
Investigative Site DE205

Langenau, 89129, Germany
Investigative Site DE206

Göttingen, 37075, Germany
Investigative Site DE207

Bad Bentheim, 48455, Germany
Investigative Site ES201

Granada, 18014, Spain
Investigative Site ES202

Las Palmas de Gran Canaria, 35010, Spain
Investigative Site ES203

Madrid, 28041, Spain
Investigative Site ES204

Santiago de Compostela, 15706, Spain
Investigative Site ES205

Barcelona, 08041, Spain
Investigative Site ES206

Granollers, 08402, Spain
Investigative Site ES207

Manises, 46940, Spain
Investigative Site ES208

Esplugues de Llobregat, 08950, Spain
Investigative Site FR201

Reims, 51100, France
Investigative Site FR202

Toulouse, 31059, France
Investigative Site FR203

Rouen, 76031, France
Investigative Site FR204

Saint-Etienne, 42055, France
Investigative Site LP204

Poznan, 60-309, Poland
Investigative Site NL201

Rotterdam, 3015 CE, Netherlands
Investigative Site NL203

Amsterdam, 1105 AZ, Netherlands
Investigative Site PL201

Rzeszów, 35-055, Poland
Investigative Site PL202

Lublin, 20-607, Poland
Investigative Site PL203

Wroclaw, 54-144, Poland
Investigative Site US201

Marriottsville, Maryland, 21104, United States
Investigative Site US202

Miami, Florida, 33173, United States
Investigative Site US203

Hialeah, Florida, 33012-3618, United States
Investigative Site US204

Portland, Oregon, 97201, United States
Investigative Site US205

Plainfield, Indiana, 46168, United States
Investigative Site US206

Maitland, Florida, 32751, United States
Investigative Site US207

Skokie, Illinois, 60077, United States
Investigative Site US208

Boca Raton, Florida, 33486, United States
Investigative Site US209

Danville, Virginia, 24541, United States
Investigative Site US210

Milwaukee, Wisconsin, 53226, United States
Investigative Site US211

Los Angeles, California, 90045, United States
Investigative Site US212

Missoula, Montana, 59804, United States
Investigative Site US213

Kew Gardens, New York, 11415, United States
Investigative Site US214

Tampa, Florida, 33609, United States
Investigative Site US215

Phoenix, Arizona, 85006, United States
Investigative Site US216

Las Vegas, Nevada, 89145, United States
Investigative Site US217

Albuquerque, New Mexico, 87102, United States
Investigative Site US218

Birmingham, Alabama, 35244, United States
Investigative Site US219

Brooklyn, New York, 11203, United States
Investigative Site US222

Fountain Valley, California, 92708, United States
Investigative Site US223

Miami, Florida, 33136, United States
Investigative Site US224

Spokane, Washington, 99202, United States
Investigative Site US225

Sandy Springs, Georgia, 30328, United States
Investigative Site US226

Plymouth Meeting, Pennsylvania, 19462, United States
Investigative Site US227

Needham, Massachusetts, 02492, United States
Investigative Site US228

Cleveland, Ohio, 44124, United States
Investigative Site US229

Norfolk, Virginia, 23502, United States
Investigative Site US230

Auburn Hills, Michigan, 48326, United States
Investigative Site US231

Columbus, Georgia, 31904, United States
Investigative Site US232

Sugar Land, Texas, 77479, United States
Investigative Site US234

Northridge, California, 91325, United States
Investigative Site US235

Hoboken, New Jersey, 07030, United States
Investigative Site US237

Los Angeles, California, 90056, United States
Investigative Site US238

Ann Arbor, Michigan, 48103, United States
Investigative Site US239

Montgomery, Alabama, 36117, United States
Investigative Site US240

Tucson, Arizona, 85718, United States
Investigative Site US241

Miami, Florida, 33147, United States
Investigative Site US242

New York, New York, 10075, United States
Investigative Site US243

Columbus, Ohio, 43213, United States
Investigative Site US244

Castle Rock, Colorado, 80109, United States
Investigative Site US245

Rochester, New York, 14620, United States
Investigative Site US246

Elmhurst, New York, 11373, United States
Investigative Site US247

Tampa, Florida, 33612, United States
Investigative Site US248

Arlington, Virginia, 22206, United States
Investigative Site US249

Columbus, Ohio, 43213, United States
Investigative Site US250

Santa Ana, California, 92706, United States
Investigative Site US251

St Louis, Missouri, 63110-1010, United States
Investigative Site US252

Cromwell, Connecticut, 06416, United States
Investigative Site US253

Milford, Massachusetts, 01757, United States
Investigative Site US254

Gambrills, Maryland, 21054, United States
Investigative Site US255

Austin, Texas, 78759, United States
Investigative Site US256

Bluffton, South Carolina, 29910, United States
Investigative Site US257

Birmingham, Alabama, 35203, United States
Investigative Site US258

Jacksonville, Florida, 32216, United States
Investigative Site US259

Huntersville, North Carolina, 28078, United States
Investigative Site US260

Cypress, Texas, 77429, United States
Investigative Site US261

Phoenix, Arizona, 85037, United States
Investigative Site US262

Encino, California, 91436, United States
Investigative Site US263

Winston-Salem, North Carolina, 27104, United States
Investigative Site US264

Lake Charles, Louisiana, 70601, United States
Investigative Site US265

Seattle, Washington, 98105, United States
Investigative Site US266

New Orleans, Louisiana, 70115, United States
Investigative Site US267

Mt. Pleasant, South Carolina, 29464, United States
Investigative Site US268

Worcester, Massachusetts, 01605, United States
Investigative Site US269

Fairport, New York, 14450, United States
Investigative Site US270

Prosper, Texas, 75078, United States
Investigative Site US271

Wildwood, Missouri, 63040, United States

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