Could a vaccine speed up TB recovery?
NCT ID NCT05455112
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a therapeutic vaccine called RUTI in 41 adults with active pulmonary tuberculosis. Participants received either the vaccine or a placebo alongside their regular antibiotic treatment. The goal was to see if the vaccine could boost the immune system to kill bacteria faster and improve recovery without causing safety issues.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
RUTI vaccine (a therapeutic vaccine made from fragments of tuberculosis bacteria)
What this could lead to
If successful, this could lead to a faster recovery from tuberculosis and reduce the risk of drug resistance.
What could go wrong
This is a small, early-phase trial (Phase IIb) with only 41 participants, so results may not apply to everyone. The vaccine is added to standard antibiotics, so its independent effect is unclear.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital José Nestor Lencinas
Godoy Cruz, Mendoza Province, M5547, Argentina
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Hospital de Clínicas Presidente Dr. Nicolás Avellaneda
San Miguel de Tucumán, Tucumán Province, T4001KKP, Argentina