TB vaccine booster shows promise in speeding up recovery
NCT ID NCT04919239
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested a therapeutic vaccine called RUTI in 140 people with tuberculosis (TB), including drug-resistant forms. Participants received either one dose of RUTI or a placebo alongside their standard TB medications. The goal was to see if the vaccine could help clear the TB bacteria from the lungs faster. Results are not yet available, but if successful, RUTI could become a tool to shorten TB treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
RUTI vaccine (therapeutic vaccination)
What this could lead to
If it works, this could shorten tuberculosis treatment and help patients clear the bacteria faster, especially those with drug-resistant TB.
What could go wrong
This is a mid-stage trial with only 140 participants. The vaccine is an add-on to standard drugs, so its benefit may be small or not seen at all. Side effects from the vaccine are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Agartala Government Medical College (AGMC)
Tripura, 799006, India
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All India Institute of Medical Sciences (AIIMS)
New Delhi, 11002, India