Cancer drug combo trial halted early – what we know

NCT ID NCT04276376

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tested a combination of two drugs, rucaparib and atezolizumab, in 130 adults with advanced solid tumors that have specific DNA repair problems or are sensitive to platinum chemotherapy. The goal was to see if the combination could shrink tumors. However, the study was terminated early, so the full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rucaparib and atezolizumab

What this could lead to

If successful, this combination could offer a new treatment option for certain hard-to-treat solid tumors.

What could go wrong

The trial was terminated early, so results are limited. It is a small, early-phase study, and the combination may not work for all tumor types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bladder transitional cell carcinoma castration-resistant prostate carcinoma gastric adenocarcinoma gastroesophageal junction adenocarcinoma metastatic prostate carcinoma non-small cell lung carcinoma nonpapillary renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gustave Roussy

    Villejuif, Val De Marne, 94800, France