Can magnetic pulses ease Schizophrenia's 'Negative' symptoms?
NCT ID NCT04318977
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help reduce negative symptoms of schizophrenia, such as lack of motivation, social withdrawal, and reduced emotional expression. Researchers are comparing two types of rTMS (high-frequency and theta burst stimulation) against a placebo in 62 adults aged 18–75 with stable medication. The main goal is to see if these treatments improve scores on a standard symptom scale.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If it works, this could offer a new way to reduce negative symptoms of schizophrenia, such as low motivation or social withdrawal.
What could go wrong
This is a small, early-stage study with only 62 participants, so results may not apply widely. The treatment is also not a cure and may not work for everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brno University Hospital
Brno, Czechia
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University Hospital Aachen
Aachen, Germany
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University Hospital Ostrava
Ostrava, Czechia
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University of Regensburg
Regensburg, Germany