Zapping the brain to reset mood and metabolism?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * (1)Signed informed consent by patient or legal representative; * (2) male or female patient aged ≧20 and ≦70 years; * (3) a diagnosis of MDD or BD according to DSM criteria made by a specialist in psychiatry; * (4) a total score of at least 18 in the Hamilton Rating Scale for Depression (HDRS) at the screening stage; * (5) patient or a reliable caregiver can be expected to ensure acceptable compliance and visit attendance for the duration of the study. Exclusion Criteria: * (1) women of childbearing potential, not using adequate contraception as per investigator judgment or not willing to comply with contraception for the duration of the study; * (2) females who are pregnant or breast-feeding; * (3) other major DSM 5 diagnoses other than mood disorders, except for tobacco use disorder and anxiety disorder; * (4) current evidence of an uncontrolled and/or clinically significant medical condition, e.g. patients with extensive area of ischemic bruise, multiple sclerosis, cardiac, hepatic and renal failure that would compromise patient safety or preclude study participation; * (5) history of seizure or epilepsy; * (6) history of neurological diseases or traumatic brain injury; * (7) history of brain lesion, having received neurosurgery, meningitis or encephalitis; * (8) exacerbation of symptom severity, presenting severe suicidal ideation or self harm behavior during the screen or study period; * (9) presence of devices, e.g. pacemakers, cochlear prosthesis, neuro-stimulators, magnetic cochlear prosthesis, intracranial/intraocular metallic fragments; * (10) patient has received electroconvulsive therapy (ECT) within 3 months prior to the first intervention of the treatment; * (11) skin lesion at local site receiving rTMS stimulation; * (12) those who cannot tolerate the side effects or ever developed sleep disorder while receiving rTMS therapy.