Brain stimulation trial targets depression in autism

NCT ID NCT07258914

Recruiting now Symptom relief Sponsor: Hospital Center Guillaume Régnier Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether repetitive transcranial magnetic stimulation (rTMS) can safely and effectively treat depression in adults with autism spectrum disorder. Twenty-five participants will receive 20 sessions of rTMS over five days. The main goal is to see if mood improves after treatment, with follow-up at one week and one month.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS)
What this could lead to: If it works, this could offer a non-invasive, well-tolerated treatment option for depression in people with autism, where standard antidepressants often fall short.
What could go wrong: This is a small, early feasibility study with only 25 participants and no control group. Results may not apply broadly, and the treatment may not prove effective.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTISM SPECTRUM DISORDER DEPRESSION MAJOR DEPRESSIVE EPISODE (MDE)

Contacts and locations

Locations

Centre Hospitalier Guillaume Régnier
RECRUITING

Rennes, 35000, France

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