New surgery eases phantom limb pain by giving nerves a muscle home
NCT ID NCT07285486
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a surgical technique called Regenerative Peripheral Nerve Interface (RPNI) in 132 leg amputees to prevent or treat painful neuromas—nerve ends that form painful growths after amputation. The procedure involves implanting the cut nerve into a small piece of muscle to give it a target, reducing the chance of neuroma formation. Researchers measured pain, medication use, and quality of life using patient surveys.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Veterans Affairs Ann Arbor Health System
Ann Arbor, Michigan, 48105, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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