New surgery eases phantom limb pain for amputees

NCT ID NCT07285486

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tested a surgical technique called Regenerative Peripheral Nerve Interface (RPNI) to prevent or treat painful nerve growths (neuromas) in people who had a leg amputated. The surgery involves placing the cut nerve end into a small piece of muscle to give the nerve a healthy place to grow. Researchers followed 132 participants and used surveys to measure pain, medication use, and quality of life.

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Contacts and locations

Locations

  • Department of Veterans Affairs Ann Arbor Health System

    Ann Arbor, Michigan, 48105, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.