New hope for transplant patients with advanced skin cancer: experimental virus therapy tested

NCT ID NCT04349436

First seen Nov 01, 2025 · Last updated Apr 26, 2026 · Updated 23 times

Summary

This study tests an experimental drug called RP1, which is injected directly into skin tumors, for people who have had an organ or stem cell transplant and now have advanced skin cancer. The goal is to see if RP1 can shrink or control the cancer while being safe for the transplanted organ. About 69 participants will receive treatment every two weeks for up to two years, with follow-up for up to three years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University

    Durham, North Carolina, 27708, United States

  • Inova Schar Cancer Institute

    Fairfax, Virginia, 22031, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic Arizona

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • Medical Dermatology Specialists

    Phoenix, Arizona, 85006, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Rochester Dermatologic Surgery

    New York, New York, 14564, United States

  • The Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • The Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • UCSF, Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, 94143, United States

  • University of California, Los Angeles

    Los Angeles, California, 90024, United States

  • University of California, San Diego

    La Jolla, California, 92093, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267, United States

  • University of Colorado Cancer Center School of Medicine

    Aurora, Colorado, 80045, United States

  • University of Miami Sylvester Comprehensive Cancer Center

    Miami, Florida, 33136, United States

  • University of North Carolina Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Tennessee Medical Center at Knoxville

    Knoxville, Tennessee, 37920, United States

  • University of Texas Southwestern

    Dallas, Texas, 75235, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.