Which root canal filler hurts less? study tests three options

NCT ID NCT07339579

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at three different root canal sealers to see if any caused less pain or helped teeth heal faster. Seventy-two adults with infected single-rooted teeth received standard root canal treatment with one of the sealers. Pain was checked right after, at 24 hours, and at 72 hours, and healing was checked after six months using X-rays and CT scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

root canal sealers (Sealapex, MTA Fillapex, AH Plus)

What this could lead to

If one sealer clearly reduces pain and speeds healing, dentists may choose it to improve patient comfort after root canals.

What could go wrong

This is a small, completed trial with only 72 patients, so results may not apply to everyone. Pain and healing vary widely between individuals.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POSTOPERATIVE PAIN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

chronic apical periodontitis Pain, Postoperative periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kahramanmaraş Sutcu İmam University, Faculty of Dentistry

    Kahramanmaraş, onikişubat, 46010, Turkey (Türkiye)