Which root canal filler hurts less? study tests three options

NCT ID NCT07339579

Completed Symptom relief Sponsor: Kahramanmaras Sutcu Imam University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at three different root canal sealers to see if any caused less pain or helped teeth heal faster. Seventy-two adults with infected single-rooted teeth received standard root canal treatment with one of the sealers. Pain was checked right after, at 24 hours, and at 72 hours, and healing was checked after six months using X-rays and CT scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: root canal sealers (Sealapex, MTA Fillapex, AH Plus)
What this could lead to: If one sealer clearly reduces pain and speeds healing, dentists may choose it to improve patient comfort after root canals.
What could go wrong: This is a small, completed trial with only 72 patients, so results may not apply to everyone. Pain and healing vary widely between individuals.

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Conditions

The condition(s) this trial relates to.

chronic apical periodontitis Pain, Postoperative periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APICAL PERIODONTITIS PERIAPICAL HEALING POSTOPERATIVE PAIN

Contacts and locations

Locations

Kahramanmaraş Sutcu İmam University, Faculty of Dentistry

Kahramanmaraş, onikişubat, 46010, Turkey (Türkiye)

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