New drug combo aims to keep rare lymphoma at bay after transplant

NCT ID NCT01908777

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving the drug romidepsin after a high-dose chemotherapy and stem cell transplant could help people with T-cell non-Hodgkin lymphoma stay in remission longer. Forty-seven patients participated. The goal was to see if this maintenance therapy improves progression-free survival at two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Romidepsin (Istodax)

What this could lead to

If successful, this approach could help keep T-cell lymphoma in remission longer after a stem cell transplant.

What could go wrong

This is a small, phase 2 study with only 47 participants. The drug may cause side effects, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for T-CELL NON-HODGKIN LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

T-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fred Hutchinson Cancer Research Center (Data Collection Only)

    Seattle, Washington, 98109, United States

  • Memorial Sloan Kettering Cancer Center

    Basking Ridge, New Jersey, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 11065, United States

  • Memorial Sloan Kettering Cancer Center @ Suffolk

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • University of Washington (Data Collection Only)

    Seattle, Washington, 98109, United States

  • Weill Cornell Medical Center

    New York, New York, United States