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New drug aims to ease tough schizophrenia symptoms

NCT ID NCT07565428

Recruiting now Symptom relief Sponsor: Minerva Neurosciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 4 times

Summary

This study tests a new drug called roluperidone for treating negative symptoms of schizophrenia, like lack of motivation and social withdrawal. About 380 adults with schizophrenia will take the drug or a placebo for 12 weeks to see if symptoms improve. Then, for 40 more weeks, researchers will compare how often symptoms return with roluperidone versus standard antipsychotics.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEGATIVE SYMPTOMS OF SCHIZOPHRENIA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Atlanta Center for Medical Research, LLC

    RECRUITING

    Atlanta, Georgia, 30331, United States

  • Behavioral Clinical Research, Inc.

    RECRUITING

    Hollywood, Florida, 33021, United States

  • CBH Health, LLC dba CenExel

    RECRUITING

    Gaithersburg, Maryland, 20877, United States

  • CenExel iResearch, LLC

    RECRUITING

    Decatur, Georgia, 30030, United States

  • Clinical Innovations, Inc. dba CITrials

    RECRUITING

    Bellflower, California, 90706, United States

  • Clinical Innovations, Inc. dba CITrials

    RECRUITING

    Riverside, California, 92506, United States

  • Collaborative Neuroscience Research, LLC

    RECRUITING

    Garden Grove, California, 92845, United States

  • ForCare Clinical Research

    RECRUITING

    Tampa, Florida, 33613, United States

  • Hassman Research Institute, LLC dba CenExel

    RECRUITING

    Marlton, New Jersey, 08053, United States

  • New York State Psychiatric Institute

    RECRUITING

    New York, New York, 10032, United States

  • Pillar Clinical Research, LLC

    RECRUITING

    Richardson, Texas, 75080, United States

  • ProScience Research Group

    RECRUITING

    Culver City, California, 90230, United States

  • Velocity Clinical Research, Hallandale Beach

    RECRUITING

    Hallandale, Florida, 33009, United States

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