Robotic arms take on breast cancer surgery: a new hope for nipple preservation?

NCT ID NCT05720039

Ongoing Disease control Sponsor: Intuitive Surgical Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a robotic surgical system (da Vinci SP) to traditional open surgery for nipple-sparing mastectomy in women with early-stage breast cancer. The trial involves 204 participants and will measure safety, cancer recurrence, and patient satisfaction. The goal is to see if the robotic approach offers similar or better outcomes with potentially less scarring.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: da Vinci SP surgical system
What this could lead to: If successful, this could show that robotic nipple-sparing mastectomy is as safe and effective as open surgery, potentially offering a less invasive option for breast cancer patients.
What could go wrong: This is a relatively early-stage trial with 204 participants, so results may not apply to all patients. Robotic surgery may have higher costs or longer procedure times, and cancer recurrence rates will need long-term follow-up.

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Conditions

The condition(s) this trial relates to.

breast cancer breast disorder breast neoplasm female breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST BREAST CANCER BREAST CANCER FEMALE BREAST CANCER, EARLY-ONSET BREAST DISEASE

Contacts and locations

Locations

Ascension St. Columbia Mary's

Milwaukee, Wisconsin, 53211, United States
Cedars-Sinai

Los Angeles, California, 940048, United States
City of Hope

Irvine, California, 92618, United States
Corewell

Detroit, Michigan, 48073, United States
Duke University

Durham, North Carolina, 27710, United States
Emory University

Atlanta, Georgia, 30342, United States
Endeavor Health

Evanston, Illinois, 60201, United States
MD Anderson Cancer Center

Houston, Texas, 77030, United States
Mayo Clinic Florida

Jacksonville, Florida, 32224, United States
Mayo Clinic Rochester

Rochester, Minnesota, 55902, United States
Northwell Health

Lake Success, New York, 11042, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19107, United States
University of Washington

Seattle, Washington, 98195, United States
Vanderbilt

Nashville, Tennessee, 37232, United States
Washington University, St. Louis

St Louis, Missouri, 63110, United States

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