New combo aims to lower dangerous side effect in blood cancer patients
NCT ID NCT04981912
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests whether giving rituximab and high-dose steroids before venetoclax can safely shrink tumors in people with relapsed chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The goal is to lower the risk of tumor lysis syndrome, a serious side effect from rapid cancer cell breakdown. About 4 adults who have already tried at least one prior treatment will participate.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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UCSD Moores Cancer Center
La Jolla, California, 92093, United States