Ultrasound may spot arthritis Flare-Ups before symptoms start

NCT ID NCT01765374

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether ultrasound could detect signs of rheumatoid arthritis (RA) relapse before symptoms appear in patients treated with rituximab. Thirty adults with RA who had not responded to at least one TNF-blocking drug were included. Researchers used ultrasound to measure joint inflammation over time, aiming to catch relapses earlier than standard clinical checks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rituximab

What this could lead to

If successful, this approach could help doctors detect rheumatoid arthritis flare-ups earlier, allowing for timely treatment adjustments.

What could go wrong

This is a small, completed Phase 4 study with only 30 participants, so results may not apply to everyone. Ultrasound detection may not reliably predict clinical symptoms.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Rheumatology

    Le Havre, 76290, France

  • Department of Rheumatology CHG Elbeuf

    Saint-Aubin-lès-Elbeuf, 76410, France

  • Department of Rheumatology, CHU de Caen

    Caen, 14033, France

  • Department of rheumatology

    Rouen, 76031, France

  • Normandy

    Caen, Le Havre, Rouen, Elbeuf, France