New hope for PMR patients: drug may reduce need for steroids

NCT ID NCT05533125

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether rituximab, a drug that calms the immune system, can help people with polymyalgia rheumatica (PMR) stop taking steroids sooner. PMR causes pain and stiffness, and steroids are the main treatment but have side effects. The trial included 114 newly diagnosed patients and compared rituximab to a placebo, with the goal of seeing if more patients could achieve remission without steroids after one year.

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Conditions

The condition(s) this trial relates to.

polymyalgia rheumatica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sint Maartensklineik

    Ubbergen, Gelderland, 6574 NA, Netherlands