Kidney disease drug combo shows promise in small trial

NCT ID NCT04743739

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding cyclosporine to rituximab is more effective than rituximab alone for treating idiopathic membranous nephropathy, a kidney disease that causes protein leakage. Only 12 adults with severe proteinuria took part before the study ended early. The goal was to see if the combination led to complete or partial remission, meaning less protein in urine and better blood protein levels.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Luhe Hospital, Capital Medical University

    Beijing, Beijing Municipality, 101149, China

  • Beijing Tongren Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100730, China

  • Fuwai Hospital, Chinese Academy of Medical Sciences

    Beijing, Beijing Municipality, 100037, China

  • Nanyang Nanshi Hospital, Henan University

    Nanyang, Henan, 473065, China

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100730, China

  • The First Affiliated Hospital of Xinjiang Medical University

    Ürümqi, Xinjiang, 830054, China

  • The Seventh Affiliated Hospital, Sun Yat-sen University

    Shenzhen, Shenzhen, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.