Second chance: could a repeat Clot-Buster save stroke patients?
NCT ID NCT07375953
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a second dose of the clot-busting drug tenecteplase can help stroke patients who don't get better within an hour of the first dose. About 120 adults with acute ischemic stroke will receive either a second dose or standard care. The goal is to see if the extra dose is safe and improves recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tenecteplase (a clot-busting drug)
What this could lead to
If it works, this could offer a rescue treatment for stroke patients who don't respond to the first clot-busting drug, potentially reducing disability.
What could go wrong
This is a small, early-phase trial (120 people) testing safety and feasibility. The second dose may increase bleeding risk, and results may not apply to all stroke patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Yu Cui
RECRUITINGShenyang, None Selected, 110840, China
Contact Phone: •••-•••-•••• Email: •••••@•••••