New Long-Acting shot for schizophrenia shows promise in small study

NCT ID NCT00526877

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a long-acting injectable form of risperidone (Risperdal Consta) in 31 people with schizophrenia or schizoaffective disorder who were already receiving home-care treatment. Participants switched from their usual antipsychotic medication to receive a shot every two weeks for 24 weeks. The goal was to see if the long-acting injection could effectively control symptoms and be safe, using standard rating scales to measure changes in symptoms and social functioning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Risperidone (long-acting injectable)

What this could lead to

If successful, this could offer a more convenient treatment option for people with schizophrenia or schizoaffective disorder, potentially improving medication adherence and symptom control.

What could go wrong

This is a small, completed Phase 4 study with only 31 participants, so results may not apply to everyone. Long-acting antipsychotics can have side effects like movement disorders or metabolic changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Psychotic Disorders schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan