New pill could tame overactive thyroid in Graves' disease

NCT ID NCT06984627

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 25 times

Summary

This study tests a new drug called rilzabrutinib in 30 adults with Graves' disease, a condition where the thyroid makes too much hormone. The goal is to see if the drug can safely lower thyroid hormone levels and improve symptoms. Participants will take one of two doses for 16 weeks and be monitored closely.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Investigational Site Number : 1240001

    RECRUITING

    Sherbrooke, Quebec, J1H 5N4, Canada

  • Investigational Site Number : 1240002

    RECRUITING

    Surrey, British Columbia, V3T 2V6, Canada

  • Investigational Site Number : 1240003

    RECRUITING

    Calgary, Alberta, T2N 4L7, Canada

  • Investigational Site Number : 2760001

    RECRUITING

    Frankfurt, 60590, Germany

  • Investigational Site Number : 2760002

    RECRUITING

    Essen, 45147, Germany

  • Investigational Site Number : 3800001

    RECRUITING

    Milan, Milano, 20122, Italy

  • Investigational Site Number : 3800002

    RECRUITING

    Pisa, 56126, Italy

  • Investigational Site Number : 3800003

    RECRUITING

    Palermo, 90127, Italy

  • Investigational Site Number : 7240001

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Investigational Site Number : 7240002

    RECRUITING

    Barcelona, Catalunya [Cataluña], 08036, Spain

  • Investigational Site Number : 7240004

    RECRUITING

    Seville, Sevilla, 41009, Spain

  • Investigational Site Number : 8260001

    RECRUITING

    Newcastle upon Tyne, England, NE2 4HH, United Kingdom

  • Investigational Site Number : 8260003

    RECRUITING

    Milton Keynes, Buckinghamshire, MK6 5LD, United Kingdom

Conditions

Explore the condition pages connected to this study.