Tooth-Derived graft material tested for better jawbone preservation
NCT ID NCT06318650
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This trial tests whether a graft made from donated teeth (allogeneic dentin matrix) can preserve the jawbone's shape and volume after a tooth extraction as well as or better than a standard bone graft. Adults aged 20–55 with a single-rooted tooth that cannot be saved and has healthy surrounding bone may join. Participants receive either the dentin graft or the bone graft immediately after extraction, and the changes in bone width and height are measured over six months using clinical exams and 3D X-rays.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
allogeneic dentin matrix
What this could lead to
If effective, this approach could offer a new, natural material for preserving jawbone shape and volume after tooth removal, potentially improving dental implant outcomes.
What could go wrong
This is a small, early-stage trial with only 22 participants. The dentin matrix may not perform better than the standard bone graft, and results may not apply to all patients.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Faculty of Dentistry Cairo University
Cairo, 12613, Egypt