Tooth-Derived graft material tested for better jawbone preservation

NCT ID NCT06318650

Completed Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This trial tests whether a graft made from donated teeth (allogeneic dentin matrix) can preserve the jawbone's shape and volume after a tooth extraction as well as or better than a standard bone graft. Adults aged 20–55 with a single-rooted tooth that cannot be saved and has healthy surrounding bone may join. Participants receive either the dentin graft or the bone graft immediately after extraction, and the changes in bone width and height are measured over six months using clinical exams and 3D X-rays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: allogeneic dentin matrix
What this could lead to: If effective, this approach could offer a new, natural material for preserving jawbone shape and volume after tooth removal, potentially improving dental implant outcomes.
What could go wrong: This is a small, early-stage trial with only 22 participants. The dentin matrix may not perform better than the standard bone graft, and results may not apply to all patients.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOCKET PRESERVATION

Contacts and locations

Locations

Faculty of Dentistry Cairo University

Cairo, 12613, Egypt

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