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Can a rhubarb extract help women regain bladder control?

NCT ID NCT07783841

Symptom relief Sponsor: Wuxi Maternity and Child Health Care Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time

Summary

This trial tests whether a daily tablet of rhubarb root extract (ERr 731) can reduce urinary incontinence in women aged 20 to 65. Over 12 weeks, participants take the supplement and track their symptoms using questionnaires and bladder diaries. The study aims to see if this natural extract, already used in Europe and the US, can lessen leakage and improve quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Rhubarb root extract (ERr 731), taken as one 4 mg tablet daily for 12 weeks
What this could lead to
If effective, this could offer a well-tolerated, natural option to reduce urinary incontinence and improve quality of life in women.
What could go wrong
This is an early, single-arm study without a placebo group, so results may be influenced by expectation. The extract is a supplement, not a regulated drug, and its benefit is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 112 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Meet the diagnostic criteria for urinary incontinence according to the "Guidelines for the Diagnosis and Treatment of Urinary Incontinence," with at least one episode of urinary incontinence per week in the past month; * Female, aged ≥20 years and ≤65 years; * Premenopausal participants must have a history of vaginal delivery; postmenopausal participants have no restriction on delivery mode (cesarean section is also eligible); * Have normal communication skills; * No history of urogenital system diseases prior to delivery; * Willing to participate in the study and sign the informed consent form. Exclusion Criteria: * Confirmed or clinically suspected malignant tumors or severe diseases of the heart, brain, liver, kidneys, or other vital organs; * Plan to become pregnant within 6 months; pregnant or breastfeeding women; * Patients with endometriosis; * Use of medications affecting bladder function within 2 weeks, or concomitant pathological bladder diseases; * History of pelvic floor dysfunction surgery or stress urinary incontinence surgery; * Allergy to the study product; * Urogenital system infection, chronic cough, or history of constipation; * Neuromuscular diseases caused by other factors; * Disease severity requiring surgical intervention; * Dementia or psychiatric disorders; * Refusal to sign the informed consent form; * Currently participating in other clinical trials.

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Conditions

The condition(s) this trial relates to.

Urinary Incontinence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Urinary incontinence

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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