Heat and cement: a new One-Two punch for spine cancer?

NCT ID NCT07090122

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether using radiofrequency ablation (heat to kill cancer cells) plus bone cement to stabilize the spine, followed by radiation, works better than radiation alone for people with cancer that has spread to the spine. The goal is to see if the combination reduces fractures, nerve problems, and pain. Thirty-six adults with spine metastases will be randomly assigned to receive the combination or radiation alone, and they will be followed for up to two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radiofrequency ablation and bone augmentation (bone cement) plus radiotherapy
What this could lead to
If it works, this combination could reduce fractures, spinal cord compression, and the need for additional surgeries in people with cancer that has spread to the spine.
What could go wrong
This is a very small pilot study with only 36 participants, so results may not apply to everyone. The procedure carries risks like infection, bleeding, or nerve damage.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

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