New antifungal drug's belly penetration tested in ICU patients

NCT ID NCT07093203

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how the antifungal drug rezafungin moves into the abdominal fluid of critically ill patients with a serious fungal infection after abdominal surgery. Researchers will measure drug levels in the blood and belly fluid of 20 patients. The goal is to see if enough drug reaches the infection site to guide future dosing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rezafungin

What this could lead to

If successful, this could help doctors determine the right dose of rezafungin for critically ill patients with abdominal fungal infections.

What could go wrong

This is a very small, early pharmacokinetic study (20 patients) that only measures drug levels, not treatment outcomes. It may not lead to changes in clinical practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

candidiasis candidiasis, invasive Intraabdominal Infections Torulopsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHRU de Nancy

    RECRUITING

    Vandœuvre-lès-Nancy, Lorraine, 54500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••