New antifungal drug's belly penetration tested in ICU patients

NCT ID NCT07093203

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how the antifungal drug rezafungin moves into the abdominal fluid of critically ill patients with a serious fungal infection after abdominal surgery. Researchers will measure drug levels in the blood and belly fluid of 20 patients. The goal is to see if enough drug reaches the infection site to guide future dosing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
rezafungin
What this could lead to
If successful, this could help doctors determine the right dose of rezafungin for critically ill patients with abdominal fungal infections.
What could go wrong
This is a very small, early pharmacokinetic study (20 patients) that only measures drug levels, not treatment outcomes. It may not lead to changes in clinical practice.

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Conditions

The condition(s) this trial relates to.

candidiasis candidiasis, invasive Intraabdominal Infections Torulopsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHRU de Nancy

    RECRUITING

    Vandœuvre-lès-Nancy, Lorraine, 54500, France

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