Eye stroke treatment put to the test: can clot busters save sight?
NCT ID NCT04965038
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether giving a clot-busting drug (tenecteplase or alteplase) within 4.5 hours of an eye stroke could restore vision. Eye stroke, or central retinal artery occlusion, is a blockage in the eye's main artery that often causes permanent vision loss. The trial aimed to enroll 127 people but was terminated early, so its findings are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tenecteplase or Alteplase (clot-busting drugs given intravenously)
- What this could lead to
- If effective, this could provide a proven emergency treatment for eye stroke, potentially restoring vision in many patients.
- What could go wrong
- The trial was terminated early, so results are limited. The treatment carries a risk of bleeding, and its benefit remains unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Tuebingen
Tübingen, 72076, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.