Can light exercise with blood flow cuffs help PAD patients walk better?

NCT ID NCT07223437

Recruiting now Symptom relief Sponsor: University of Tennessee Graduate School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special exercise program using blood flow restriction cuffs can improve walking ability and quality of life in people with peripheral arterial disease (PAD). About 81 adults with stable leg pain from PAD will do low-intensity calf raises while wearing cuffs that limit blood flow. Researchers will measure walking distance, symptoms, and safety over 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Blood Flow Restriction Cuff System
What this could lead to: If it works, this could offer a new, low-intensity exercise option to help people with PAD walk farther and feel better.
What could go wrong: This is a small feasibility study, so results may not apply broadly. The exercise involves temporary blood flow restriction, which may cause discomfort or leg pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PERIPHERAL ARTERIAL DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIPHERAL ARTERIAL DISEASE

Contacts and locations

Locations

University of Tennessee Medical Center
RECRUITING

Knoxville, Tennessee, 37920, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.