New drug tested to protect kidneys in overweight patients

NCT ID NCT05936151

Summary

This study tested whether an investigational drug called retatrutide could improve kidney function in people who are overweight or obese and have chronic kidney disease, with or without type 2 diabetes. The 31-week trial involved 146 participants and compared the drug's effects to a placebo. Researchers measured changes in key kidney health markers, including filtration rate and protein in urine, to see if the treatment could help control the progression of kidney disease.

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Contacts and locations

Locations

  • 9109-0126 Quebec Inc.

    Montreal, Quebec, H4N 2W2, Canada

  • Addenbrooke's Hospital

    Cambridge, Cambridgeshire, CB2 2QQ, United Kingdom

  • Azienda Ospedaliera Universitaria Pisana

    Pisa, Tuscany, 56126, Italy

  • Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII

    Bergamo, 24127, Italy

  • Care Access - 801 South Power Road, Mesa

    Mesa, Arizona, 85206, United States

  • Catalina Research Institute, LLC

    Montclair, California, 91763, United States

  • Centricity Research Brampton Endocrinology

    Brampton, Ontario, L6S 0C6, Canada

  • Centro Cardiologico Monzino

    Milan, Milano, 20138, Italy

  • Circulate Cardiac & Vascular Centre

    Burlington, Ontario, L7M 1K9, Canada

  • City Hospital, Nottingham University Hospitals NHS Trust

    Nottingham, NG5 1PB, United Kingdom

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Clínica nuevas Tecnologías en Diabetes y Endocrinología (NTDE)

    Seville, 41003, Spain

  • Diex Recherche Joliette

    Joliette, Quebec, J6E 6A9, Canada

  • Dr. Anil K. Gupta Medicine Professional Corporation

    Toronto, Ontario, M9V 4B4, Canada

  • Endocrine Ips, Pllc

    Houston, Texas, 77079, United States

  • Fadia El Boreky Medicine

    Waterloo, Ontario, N2J 1C4, Canada

  • FutureMeds Teesside - Middlefield Centre

    Stockton-on-Tees, Durham County, TS19 8PE, United Kingdom

  • Futuremeds-Newcastle

    Newcastle, England, United Kingdom

  • Great Lakes Clinical Trials - Ravenswood

    Chicago, Illinois, 60640, United States

  • Headlands Research - Scottsdale

    Scottsdale, Arizona, 85260, United States

  • Hope Clinical Research, Inc.

    Canoga Park, California, 91303, United States

  • Hospital Clinico de Valencia

    Valencia, Valenciana, Comunitat, 46010, Spain

  • Hospital Universitario Doctor Peset

    Valencia, Valenciana, Comunitat, 46017, Spain

  • Indiana University Health University Hospital

    Indianapolis, Indiana, 46202, United States

  • Medical Advancement Centers of Arizona

    Tempe, Arizona, 85283, United States

  • NYU Langone Hospital - Long Island

    Mineola, New York, 11501, United States

  • North Middlesex Hospital

    London, London, City of, N18 1QX, United Kingdom

  • North York Diagnostic and Cardiac Centre

    North York, Ontario, M6B 3H7, Canada

  • Ospedale San Raffaele

    Milan, 20132, Italy

  • Palm Research Center Tenaya

    Las Vegas, Nevada, 89128, United States

  • Peninsula Research Associates

    Rolling Hills Estates, California, 90274, United States

  • Prime Health and Wellness/SKYCRNG

    Fayette, Mississippi, 39069, United States

  • Royal London Hospital

    London, England, E1 1BB, United Kingdom

  • Stouffville Medical Research Institute Inc.

    Stouffville, Ontario, L4A 1H2, Canada

  • Suncoast Clinical Research, Inc.

    New Port Richey, Florida, 34652, United States

  • Teradan Clinical Trials, LLC

    Brandon, Florida, 33511, United States

  • The Institute for Liver Health II dba Arizona Clinical Trials - Mesa

    Chandler, Arizona, 85225, United States

  • Tranquility Research

    Webster, Texas, 77598, United States

  • University of Colorado Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

  • Vascular Research Team

    Salford, Greater Manchester, M6 8HD, United Kingdom

  • Viacar Recherche Clinique

    Greenfield Park, Quebec, J4V 2G8, Canada

  • Victorium Clinical Research - Houston

    Houston, Texas, 77024, United States

Conditions

Explore the condition pages connected to this study.