Can a pill turn back the clock? scientists test Anti-Aging drugs in seniors

NCT ID NCT06658093

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study is testing two drugs, rapamycin and everolimus, in 194 healthy adults aged 65 to 90. The goal is to find a safe dose and timing that can reduce a key aging signal in cells to levels seen in younger people. The researchers also want to see if the best dose differs between men and women.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rapamycin (sirolimus) and everolimus (Afinitor), both mTOR inhibitors

What this could lead to

If successful, this study could identify safe doses of these drugs that mimic the cellular activity of younger people, potentially pointing toward a way to slow aging and reduce age-related diseases.

What could go wrong

This is a very early, exploratory trial focused on dosing and safety, not on proving that the drugs actually slow aging in humans. The results may not translate to real-world benefits, and mTOR inhibitors have known side effects like immune suppression and mouth sores.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas Health Science Center at San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••