New Sound-Based device could revolutionize fluid management in surgery

NCT ID NCT07516470

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jul 17, 2026 · Updated 4 times

Summary

This trial tests a new device called ResQ that listens to heart and lung sounds through a soft probe in the esophagus to predict if a patient needs more fluids during surgery. Researchers will compare its accuracy to the standard method using an arterial line. The study involves 122 adults undergoing major abdominal or pelvic surgery under general anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ResQ device (acoustic variability index monitor)
What this could lead to
If successful, this could provide a less invasive way to guide fluid management during surgery, potentially reducing complications.
What could go wrong
This is a small, early-stage trial with only 122 participants, so results may not apply to all patients. The device may not be as accurate as standard methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

122 people

The number who actually took part.

Started

Apr 2026

Finished

Jul 2026

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients at Asan Medical Center in Seoul, South Korea. Participants will be recruited from the patients scheduled to undergo elective major surgeries involving organs in the abdominal, retroperitoneal, or pelvic cavities (such as hepatobiliary, pancreatic, intestinal, renal, or uterine procedures). These patients will be receiving general anesthesia and mechanical ventilation and are expected to require continuous intraoperative hemodynamic monitoring as part of their standard surgical care.

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: To participate in this study, individuals must meet all of the following criteria: * Adults aged 19 years or older. * If female, not pregnant or breastfeeding. * Scheduled for a planned surgery of major organs in the abdominal, retroperitoneal, or pelvic cavities (e.g., hepatobiliary and pancreatic, small intestine, large intestine, kidney, uterus) under general anesthesia with mechanical ventilation * Classified as American Society of Anesthesiologists (ASA) Class I, II, or III. (Note: Excluded regardless of class if any exclusion criteria are met) * Scheduled to receive mechanical ventilation in a volume-controlled or pressure-controlled mode in the operating room or intensive care unit, with an anticipated tidal volume of 6-8 mL/kg (Ideal Body Weight), respiratory rate of 8-14 breaths/min, and PEEP of 0-5 cmH2O * Scheduled for hemodynamic monitoring to measure the comparison indices during surgery * Able to understand the study's purpose and procedures and communicate clearly with the investigator and research staff * Voluntarily signed the written informed consent form before participating in the study Exclusion Criteria: Individuals meeting any of the following criteria will be excluded from participation: * Undergoing emergency or unplanned surgery * Anticipated to have difficulty with the application of general anesthesia or mechanical ventilation * Anticipated to experience massive bleeding of 1 L or more during surgery. * Undergoing a reoperation due to the same underlying disease * History of severe esophageal damage (e.g., esophageal varices or stricture) that makes inserting the probe difficult * Inability to have an arterial catheter inserted, making the measurement of Stroke Volume Variation (SVV) and Pulse Pressure Variation (PPV) difficult * Condition where a fluid challenge is contraindicated or considered high risk (e.g., clinical signs of fluid overload, pulmonary congestion, or pulmonary edema; acute exacerbation of heart failure or renal failure; or a hemodynamically unstable state) * Body Mass Index (BMI) greater than 30 kg/m² * Uncontrolled coagulopathy prior to surgery (e.g., Platelet count \< 100,000/μL or INR \> 2) * Arrhythmias, such as atrial fibrillation/flutter or premature atrial/ventricular contractions (\>2 per 10 seconds), that make it difficult for the variability index to operate accurately * Other cardiovascular history that makes accurate cardiac output measurement impossible (e.g., severe valvular disease, history of intracardiac shunt surgery, or structural heart surgery) * Pregnant or lactating women * Any other condition deemed unsuitable for study participation by the investigator

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, Seoul, 05505, South Korea

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