New study tests if gentle exercise with Arm/Leg cuffs can boost muscle in obesity
NCT ID NCT07444736
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether 8 weeks of resistance training with blood flow restriction can improve muscle strength, body measurements, and health markers in adults with obesity. Thirty participants aged 18 to 40 with a BMI between 30 and 40 will do leg and arm exercises using light weights while wearing a cuff that partially restricts blood flow. Researchers will measure changes in strength, blood pressure, cholesterol, inflammation, and more.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- resistance training with blood flow restriction
- What this could lead to
- If it works, this could offer a time-efficient exercise method to improve muscle strength and metabolic health in people with obesity.
- What could go wrong
- This is a small, early-phase study with only 30 participants, so results may not apply to everyone. The blood flow restriction technique may cause discomfort or rare risks like bruising or blood clots.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 40 * Both genders * BMI ≥ 30 kg/m\^2 and \< 40 kg/m\^2 * Signed informed consent form Exclusion Criteria: * Participants who smoke * Personal and family history of vascular disease or deep vein thrombosis * Clinical diagnosis of hypothyroidism * Clinical diagnosis of type 1 diabetes mellitus * Clinical diagnosis of type 2 diabetes mellitus * Clinical diagnosis of grade 3 obesity * Clinical diagnosis of hypertension * Clinical diagnosis of acute myocardial infarction or angina pectoris * Use of nitrates and calcium channel blockers within 4 days prior to the start of the study * Use of anticoagulants * Use of beta-blockers or hypoglycemic agents within 7 days prior to the intervention * Pregnant women * Breastfeeding women * Men consuming more than 40 g of alcohol per day or women consuming more than 20 g per day * Postural and biomechanical disorders (knee, foot, and spine)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centro Universitario de Tlajomulco
Tlajomulco de Zúñiga, Jalisco, 45650, Mexico
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