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Promising drug targets lung cancer brain tumors in early trial

NCT ID NCT06315010

Recruiting now Disease control Sponsor: MedSIR Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called repotrectinib in 20 people with a specific type of lung cancer (ROS1-positive NSCLC) that has spread to the brain. The main goal is to see if the drug can shrink or eliminate brain tumors. Participants will take the drug by mouth, and doctors will monitor safety and how well it works against both brain and body tumors.

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Conditions

The condition(s) this trial relates to.

brain cancer metastatic malignant neoplasm in the brain non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN METASTASES NSCLC ROS1 GENE REARRANGEMENT

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Complejo Hospitalario Universitario de Santiago (CHUS)

    RECRUITING

    Santiago de Compostela, 15706, Spain

  • Hospital Beata María Ana

    RECRUITING

    Madrid, 28007, Spain

  • Hospital Clínico Universitario de Valencia

    RECRUITING

    Valencia, 46010, Spain

  • Hospital General Universitario Dr. Balmis

    RECRUITING

    Alicante, 03010, Spain

  • Hospital Lucus Agusti

    RECRUITING

    Lugo, 27003, Spain

  • Hospital Universitari Sant Joan de Reus

    RECRUITING

    Reus, Tarragona, 43204, Spain

  • Hospital Universitari Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario Vithas Madrid La Milagrosa

    RECRUITING

    Madrid, 28010, Spain

  • Hospital Universitario de León

    RECRUITING

    León, 24008, Spain

  • Hospital de Cruces

    RECRUITING

    Barakaldo, 48903, Spain

  • Hospital de Vinalopó

    RECRUITING

    Elche, Alicante, 03293, Spain

  • Institut Català d' Oncologia Girona (ICO)

    RECRUITING

    Girona, 17007, Spain

  • Ludwig-Maximilians-University Munich

    RECRUITING

    München, Germany

  • Medical University of Vienna

    RECRUITING

    Vienna, Austria

  • Medizinische Universität Graz

    RECRUITING

    Graz, 8010, Austria

  • UOMI Cancer Center

    RECRUITING

    Barcelona, 08017, Spain

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