Double dose of numbing drug may slash opioid need after sarcoma surgery

NCT ID NCT04189783

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether giving a second numbing injection (quadratus lumborum block) after surgery for retroperitoneal sarcoma can reduce the need for opioid painkillers. About 113 patients will receive either one or two injections of liposomal bupivacaine. The goal is to see if the extra shot helps more patients leave the hospital without an opioid prescription, lowering the risk of long-term use or addiction.

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Conditions

The condition(s) this trial relates to.

retroperitoneal sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States