Ultrasound clue could flag which ICU patients need dialysis

NCT ID NCT06995222

Completed Diagnosis Sponsor: Gulhane Training and Research Hospital Source: ClinicalTrials.gov ↗

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive ultrasound measurement called the renal resistive index (RRI) can predict if acute kidney injury (AKI) will progress to a severe stage in intensive care unit (ICU) patients. Researchers will measure RRI in 120 adults with early-stage AKI within 24 hours of ICU admission and track their kidney function daily. The goal is to see if RRI can identify patients who may need renal replacement therapy (dialysis) and to assess its link to mortality at 14 and 28 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Renal resistive index measurement using Doppler ultrasound
What this could lead to: If effective, this non-invasive ultrasound measure could help doctors predict which ICU patients with kidney injury will worsen and need dialysis, enabling earlier intervention.
What could go wrong: The trial is relatively small and early, and the renal resistive index's reliability in this setting is debated. It may not accurately predict outcomes for all patients.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AKUT KIDNEY INJURY RENAL REPLACEMENT THERAPY FOR ACUTE KIDNEY INJURY IN ICU

Contacts and locations

Locations

Gulhane Education and Research Hospital Ankara Türkiye

Ankara, Türkiye, 06010, Turkey (Türkiye)

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