Can a new anesthetic give older surgery patients a better Night's sleep?

NCT ID NCT07740343

First seen Jul 31, 2026 ยท Last updated Jul 31, 2026

Summary

This trial tests whether remimazolam, an anesthetic drug, can improve sleep quality in older adults after laparoscopic colorectal cancer surgery, compared with the standard anesthetic propofol. Participants aged 65-80 will be randomly assigned to receive one of the two anesthetics during surgery. Sleep will be measured objectively using polysomnography (a gold-standard sleep test) on the first night after surgery, along with subjective sleep questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
remimazolam
What this could lead to
If remimazolam preserves sleep quality better than propofol, it could become a preferred anesthetic for elderly patients, potentially aiding recovery after major surgery.
What could go wrong
This is a small, early-stage trial, and results may not apply to all patients. Sleep outcomes can vary widely, and the drug's benefits over propofol remain unproven.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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