New hope for kids with rare epilepsy: drug trial targets seizure control

NCT ID NCT07010471

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an investigational drug called relutrigine in 160 children with a severe form of epilepsy called developmental and epileptic encephalopathy (DEE). The goal is to see if the drug can safely reduce monthly seizure frequency compared to a placebo. After the initial blinded phase, all participants can receive the drug in an open-label extension.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

developmental and epileptic encephalopathy developmental and epileptic encephalopathy, 1 epilepsy infantile epileptic-dyskinetic encephalopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Praxis Research Site

    RECRUITING

    La Jolla, California, 92037, United States

  • Praxis Research Site

    RECRUITING

    Gulf Breeze, Florida, 32561, United States

  • Praxis Research Site

    RECRUITING

    Chevy Chase, Maryland, 20815, United States

  • Praxis Research Site

    RECRUITING

    Roseville, Minnesota, 55113, United States

  • Praxis Research Site

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Praxis Research Site

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Praxis Research Site

    RECRUITING

    Heidelberg, Victoria, 3084, Australia

  • Praxis Research Site

    RECRUITING

    Rio Grande, Do Sul, 90610, Brazil

  • Praxis Research Site

    RECRUITING

    Paraná, 80250, Brazil

  • Praxis Research Site

    RECRUITING

    Rio de Janeiro, 20231, Brazil

  • Praxis Research Site

    RECRUITING

    São Paulo, 15090, Brazil