Triple-Drug cocktail shows promise for Hard-to-Treat colorectal cancer
NCT ID NCT04362839
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times
Summary
This early-phase study tested a combination of three drugs—regorafenib, nivolumab, and ipilimumab—in 39 people with advanced colorectal cancer that had spread and was no longer responding to chemotherapy. The goal was to find the safest dose and see if the combination could slow tumor growth by blocking cancer cell signals and boosting the immune system. The study focused on side effects and tumor response, not a cure, and participants may need ongoing treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
Conditions
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